Peer-Reviewed Scholarship in Print or Other Media
Research Investigations
- Gringras P, Anilkumar A, Bray L, Carter B, Coffey T, Cook G, Crudgington H, Currier J, Dietz K, Hardy W, Hiscock H, Hughes D, Morris C, Pal DK, Roberts D, Rouncefield Swales A, Saron H, Spowart C, Stibbs Eaton L, Tudur Smith C, Watson V, Whittle L, Wiggs L. Clinical and cost effectiveness of an online parent led behavioural sleep intervention (COSI) within paediatric epilepsy services across the UK: the CASTLE Sleep E multicentre randomised controlled trial (preprint). medRxiv. 2025; 05.14.25326746. PMID: [Preprint – no PMID].
- Paton C, Gringras P, Ruan A, Liew A, Rendora O, Bove G, Barnes TRE. Quality of melatonin use in children and adolescents – findings from a UK clinical audit. BMJ Mental Health. 2024; 27(1): e300894. PMID: 39093720.
- Ipsiroglu OS, Klösch G, Blunden S, Gringras P, Stein PS, Mehler B. Phenotyping sleep disturbances in ADHD and identifying harmonised outcome measures – a personalised precision medicine approach to disruptive behaviours. Somnologie. 2024; 28: 313–327. DOI: 10.1007/s11818-024-00473-4. PMID: [Not indexed].
- Cameron S, Donnelly A, Broderick C, Arichi T, Bartsch U, Dazzan P, Elberling J, Godfrey EM, Gringras P, Heathcote LC, Joseph D, Wood TC, Pariante C, Rubia K, Flohr C. Mind and skin – exploring links between inflammation, sleep disturbance and neurocognitive function in atopic dermatitis. Allergy. 2024; 79(1): 26–36. PMID: 37469218.
- Cook G, Bray L, Carter B, Gringras P, Morris C, Pal DK, Saron H, Tudur Smith C, Wiggs L. A cross sectional survey of healthcare professionals supporting children and young people with epilepsy and their parents/carers – topics raised in clinic and perceived support. Epilepsy & Behavior. 2023; 149: 109543. PMID: 38006842.
- Jones S, Hanwell R, Chowdhury T, Orgill J, VanDenEshof K, Farquhar M, Joseph D, Gringras P, Trucco F. Feasibility and parental perception of home sleep studies during COVID 19 – a tertiary sleep centre experience. Archives of Disease in Childhood. 2022; 107(2): 189–191. PMID: 34551900.
- Malow BA, Findling RL, Schroder CM, Maras A, Breddy J, Nir T, Zisapel N, Gringras P. Sleep, growth and puberty after 2 years of prolonged release melatonin in children with autism spectrum disorder. Journal of the American Academy of Child & Adolescent Psychiatry. 2021; 60(2): 252–261. PMID: 31982581.
- Kose C, Wood I, Gwyther A, Basnet S, Gaskell C, Gringras P, Elphick HE, Evans H, Hill CM. Sleep related rhythmic movement disorder in young children with Down syndrome – prevalence and clinical features. Brain Sciences. 2021; 11(10): 1326. PMID: 34679391. DOI: 10.3390/brainsci11101326.
- Stowe J, Andrews N, Gringras P, Quinnell T, Zaiwalla Z, Shneerson J, Miller E. Reassessment of the risk of narcolepsy in children in England 8 years after receipt of the AS03 adjuvanted H1N1 pandemic vaccine – a case coverage study. PLOS Medicine. 2020; 17(9): e1003225. PMID: 32926731.
- Kingshott RN, Gahleitner F, Elphick HE, Gringras P, Farquhar M, Pickering RM, Martin J, Reynolds J, Joyce A, Gavlak JC, Evans HJ, Hill CM. Cardiorespiratory sleep studies at home – experience in research and clinical cohorts. Archives of Disease in Childhood. 2019; 104(5): 476–481. PMID: 30455364. DOI: 10.1136/archdischild-2018-315676.
- Schroder CM, Malow BA, Maras A, Melmed RD, Findling RL, Breddy J, Nir T, Shahmoon S, Zisapel N, Gringras P. Paediatric prolonged release melatonin in ASD – impact on behaviour and caregiver quality of life. Journal of Autism and Developmental Disorders. 2019; 49(8): 3218–3230. PMID: 31079275.
- Yau S, Pickering RM, Gringras P, Elphick HE, Evans H, Farquhar M, Martin J, Joyce A, Reynolds J, Kingshott RN, Mindell JA, Hill CM. Sleep in infants and toddlers with Down syndrome compared to typically developing peers – looking beyond snoring. Sleep Medicine. 2019; 63: 88–97. PMID: 31606654.
- Hill CM, Elphick HE, Farquhar M, Gringras P, Pickering RM, Kingshott RN, Martin J, Reynolds J, Joyce A, Gavlak JC, Evans HJ. Home oximetry to screen for obstructive sleep apnoea in Down syndrome. Archives of Disease in Childhood. 2018; 103(10): 962–967. PMID: 29760010. DOI: 10.1136/archdischild-2017-314409.
- Maras A, Schroder CM, Malow BA, Findling RL, Breddy J, Nir T, Shahmoon S, Zisapel N, Gringras P. Long term efficacy and safety of paediatric prolonged release melatonin in ASD. Journal of Child and Adolescent Psychopharmacology. 2018; 28(10): 699–710. PMID: 30132686.
- Collin SM, Norris T, Gringras P, Blair PS, Tilling K, Crawley E. Childhood sleep and adolescent chronic fatigue syndrome – evidence of associations in a UK birth cohort. Sleep Medicine. 2018; 46: 26–36. PMID: 29773208.
- Rossor T, Lim M, VanDenEshof K, Gringras P. Pseudotumor cerebri syndrome in a patient with narcolepsy type 1. European Journal of Paediatric Neurology. 2018; 22(1): 194–198. PMID: 29195824. DOI: 10.1016/j.ejpn.2017.11.002.
- Almandil NB, Aleisa AM, Al Jaser MA, Berthebaud N, Chami N, Harrison JE, Gringras P, Wong ICK, Aitchison KJ, Al Jefri AM. Associations between the LEP −2548G/A promoter and baseline weight and between LEPR Gln223Arg and Lys656Asn variants and change in BMI z scores in Arab children and adolescents treated with risperidone. Molecular Neuropsychiatry. 2018; 4(2): 111–117. PMID: 30397599.
- Colonna A, Smith AB, Smith S, VanDenEshof K, Orgill J, Gringras P, Pal D. The effects of sleep on emotional target detection in children and adolescents. Frontiers in Psychology. 2018; 9: 241. PMID: 29563887. DOI: 10.3389/fpsyg.2018.00241.
- Gringras P, Nir T, Breddy J, Frydman Marom A, Findling RL. Efficacy and safety of paediatric prolonged release melatonin for insomnia in children with autism spectrum disorder. Journal of the American Academy of Child & Adolescent Psychiatry. 2017; 56(11): 948–957. PMID: 29096777.
- Rosch RE, Farquhar M, Gringras P, Pal DK. Narcolepsy following yellow fever vaccination – a case report. Frontiers in Neurology. 2016; 7: 130. PMID: 27559330.
- Hill CM, Evans HJ, Elphick HE, Farquhar M, Pickering RM, Kingshott RN, Martin J, Reynolds J, Joyce A, Rush C, Gavlak JC, Gringras P. Prevalence and predictors of obstructive sleep apnoea in young children with Down syndrome. Sleep Medicine. 2016; 27–28: 99–106. PMID: 27938928. DOI: 10.1016/j.sleep.2016.10.001.
- Davidson J, Gringras P, Fairhurst C, Simpson J. Physical and neurodevelopmental outcomes in children with single ventricle circulation. Archives of Disease in Childhood. 2015; 100(5): 449–453. PMID: 25480924.
- El Kersh K, Jungbluth H, Gringras P, Senthilvel E. Severe central sleep apnoea in Vici syndrome. Pediatrics. 2015; 136(5): e1390–e1394. PMID: 26482670. DOI: 10.1542/peds.2015-0297.
- Santosh P, Gringras P, Baird G, Fiori F, Sala R. Development and psychometric properties of the parent version of the Profile of Neuropsychiatric Symptoms (PONS) in children and adolescents. BMC Pediatrics. 2015; 15: 62. PMID: 25986431. DOI: 10.1186/s12887-015-0376-x.
- Gringras P, Green D, Wright B, Rush C, Sparrowhawk M, Pratt K, Allgar V, Hooke N, Moore D, Zaiwalla Z, Wiggs L. Weighted blankets and sleep in autistic children – a randomised controlled trial. Pediatrics. 2014; 134(2): 298–306. PMID: 25022743.
- Humphreys JS, Gringras P, Blair PS, Scott N, Henderson J, Fleming PJ, Emond AM. Sleep patterns in children with autistic spectrum disorders – a prospective cohort study. Archives of Disease in Childhood. 2014; 99(2): 114–118. PMID: 24061777.
- Scott N, Blair PS, Henderson J, Fleming PJ, Emond AM, Gringras P. Sleep patterns in children with attention deficit/hyperactivity disorder – a population based cohort study from birth to 11 years. Journal of Sleep Research. 2013; 22(3): 294–303. PMID: 23057438.
- Blair PS, Gringras P, Taheri S, Scott N, Emond AM, Henderson J, Fleming PJ. Childhood sleep duration and associated demographic characteristics in a large UK cohort. Sleep. 2012; 35(3): 353–360. PMID: 22379241.
- Pratt K, Baird G, Gringras P. Ensuring successful admission to hospital for young people with learning difficulties, autism and challenging behaviour – a continuous quality improvement and change management programme. Child: Care, Health and Development. 2012; 38(6): 789–797. PMID: 22017703.
- Webb EA, O’Reilly MA, Orgill J, Dale N, Salt A, Gringras P, Dattani MT. Rest–activity disturbances in children with septo–optic dysplasia characterised by actigraphy and 24 hour plasma melatonin profiles. Journal of Clinical Endocrinology & Metabolism. 2010; 95(10): E198–E203. PMID: 20660044.
- Edmonds CJ, Isaacs EB, Cole TJ, Rogers MH, Lanigan J, Singhal A, Birbara T, Gringras P, Denton J, Lucas A. The effect of intrauterine growth on verbal IQ scores in childhood – a study of monozygotic twins. Pediatrics. 2010; 126(5): e1095–e1101. PMID: 20937654. DOI: 10.1542/peds.2008-3684.
- Cass H, Gringras P, March J, McKendrick I, O’Hare AE, Owen L, Pollin C. Absence of urinary opioid peptides in children with autism. Archives of Disease in Childhood. 2008; 93(9): 745–750. PMID: 18337276.
- Edmonds CJ, Isaacs EB, Visscher PM, Rogers M, Lanigan J, Singhal A, Lucas A, Gringras P, Denton J, Deary IJ. Inspection time and cognitive abilities in twins aged 7 to 17 years – age related changes, heritability and genetic covariance. Intelligence. 2008; 36(3): 210–225. PMID: [Not indexed].
- Shah T, Tse PYA, Gill H, Wong ICK, Sutcliffe A, Gringras P, Appleton R, Tuleu C. Administration of melatonin mixed with common soft food and liquids to children with neurodevelopmental difficulties – melatonin bioavailability. Developmental Medicine & Child Neurology. 2008; 50(11): 845–849. PMID: 18754762.
- Simonoff E, Pickles A, Wood N, Gringras P, Chadwick O. ADHD symptoms in children with mild intellectual disability. Journal of the American Academy of Child & Adolescent Psychiatry. 2007; 46(5): 591–600. PMID: 17450048.
- Simonoff E, Pickles A, Chadwick O, Gringras P, Wood N, Higgins S, Maney JA, Karia N, Iqbal H, Moore A. The Croydon Assessment of Learning Study (CALS) – prevalence and educational identification of mild mental retardation. Journal of Child Psychology and Psychiatry. 2006; 47(8): 828–839. PMID: 16898997.
- Santosh PJ, Baird G, Pityaratstian N, Tavare E, Gringras P. Impact of comorbid autism spectrum disorders on stimulant response in children with attention deficit/hyperactivity disorder – a retrospective and prospective effectiveness study. Child: Care, Health and Development. 2006; 32(5): 575–583. PMID: 16919137.
- Gringras P, Santosh P, Baird G. Development of an internet based, real time system for monitoring pharmacological interventions in children with neuropsychiatric disorders. Child: Care, Health and Development. 2006; 32(5): 591–600. PMID: 16919139.
- Waldron DL, Bramble D, Gringras P. Melatonin – prescribing practices and adverse events. Archives of Disease in Childhood. 2005; 90(11): 1206–1207. PMID: 16243894.
- Koeppen Schomerus G, Eley TC, Wolke D, Gringras P, Plomin R. The interaction of prematurity with genetic and environmental influences on cognitive development in twins. Journal of Pediatrics. 2000; 137(4): 527–533. PMID: 11035833.
- Gringras P. Identical differences – phenotypic differences in monozygotic twins. Lancet. 1999; 353(9152): 562. PMID: 10028995.
- Gringras P, Barnicoat A. Retesting for fragile X syndrome in cytogenetically normal males. Developmental Medicine & Child Neurology. 1998; 40: 62–64. PMID: 9459219.
Other Peer Reviewed Scholarship
- Melatonin Task Force; Owens J; Simakajornboon N; Kotagal S; Gringras P; IPSA Practice & Policy Committee; IPSA Board. Melatonin use in managing insomnia in typically developing children – technical report. Sleep Medicine. 2025; 128: 89–94. PMID: 39892084.
- Plazzi G, Pizza F, Lecendreux M, Gringras P, Barateau L, Bruni O, Franco P, Iranzo A, Jennum P, Khatami R, Knudsen Heier S, Miano S, Nobili L, Partinen M, Reading P, Sonka K, Szakacs A, Zenti M, Kallweit U, Lammers GJ, Dauvilliers Y, Bassetti CLA. Pharmacological management of narcolepsy in children and adolescents. Journal of Sleep Research. 2024; 33(4): e14055. PMID: 38050449.
- Al Najjar N, Bray L, Carter B, Collingwood A, Cook G, Crudgington H, Currier J, Dietz KC, Hardy WAS, Hiscock H, Hughes D, Morris C, Roberts D, Rouncefield Swales A, Saron H, Spowart C, Stibbs Eaton L, Tudur Smith C, Watson V, Whittle L, Wiggs L, Wood E, Gringras P, Pal DK. CASTLE Sleep E – protocol for a randomised controlled trial of an online behavioural sleep intervention in children with Rolandic epilepsy. BMJ Open. 2023; 13: e065769. PMID: 36898757.
- Krishnan ML, Berry Kravis E, Capal JK, Carpenter R, Gringras P, Hipp JF, Miller MT, Mingorance A, Philpot BD, Pletcher MT, Rotenberg A, Tjeertes J, Wang PP, Willgoss T, de Wit M C, Jeste SS. Clinical trial strategies for rare neurodevelopmental disorders – challenges and opportunities. Nature Reviews Drug Discovery. 2021; 20(9): 653–654. PMID: 34002058.
- Wilson S, Anderson K, Baldwin D, Dijk D J, Espie A, Espie C, Gringras P, Krystal A, Nutt D, Selsick H, Sharpley A. Evidence based treatment of insomnia, parasomnias and circadian rhythm disorders – British Association for Psychopharmacology consensus update. Journal of Psychopharmacology. 2019; 33(8): 923–947. PMID: 31271339.
- Morris C, Crudgington H, Gibbon FM, Currier J, Roberts D, Rogers M, Tudur Smith C, Williamson PR, Gringras P, Pal DK. Core Health Outcomes in Childhood Epilepsy (CHOICE) – protocol for the selection of a core outcome set. Trials. 2017; 18: 572. PMID: 29183384.
- Gringras P, Middleton B, Skene DJ, Revell VL. Bigger, Brighter, Bluer Better? Current light emitting devices – adverse sleep properties and preventative strategies. Frontiers in Public Health. 2015; 3: 233. PMCID: PMC4602096.
- Appleton RE, Gringras P. Melatonin – helping to MEND impaired sleep. Archives of Disease in Childhood. 2013; 98(3): 216–217. PMID: 23413423.
- Thebault S, Vincent A, Gringras P. Narcolepsy and H1N1 vaccination – a link?. Current Opinion in Pulmonary Medicine. 2013; 19(6): 587–593. PMID: 24048081.
- Wilson SJ, Nutt DJ, Alford C, Argyropoulos SV, Baldwin DS, Bateson AN, Britton TC, Crowe C, Dijk D J, Espie CA, Gringras P, Hajak G, Idzikowski C, Krystal AD, Nash JR, Selsick H, Sharpley AL, Wade AG. British Association for Psychopharmacology consensus statement on evidence based treatment of insomnia, parasomnias and circadian rhythm disorders. Journal of Psychopharmacology. 2010; 24(11): 1577–1601. PMID: 20813762.
- Balfour Lynn IM, Field DJ, Gringras P, Hicks B, Jardine E, Jones RC, Magee AG, Primhak RA, Samuels MP, Shaw NJ, Stevens S, Sullivan C, Taylor JA, Wallis C; BTS Standards of Care Committee. BTS guidelines for home oxygen in children. Thorax. 2009; 64 Suppl 2: ii1–ii26. PMID: 19586968.
Reviews, Chapters, Monographs & Editorials
- Gringras P. Sleep and its disturbances in autistic spectrum disorders. In: Sheldon SH, Kryger MH, Ferber R, eds. Principles and Practice of Pediatric Sleep Medicine. 2nd ed. Saunders; 2014.
- Gringras P. Sleep and its disturbances in autistic spectrum disorders. In: Sheldon SH, Kryger MH, Gozal D, Canapari D, Oyebile-Chidi TO, eds. Principles and Practice of Pediatric Sleep Medicine. 3rd ed. Elsevier; 2024.
- Gringras P. Sleep disorders and ADHD. In: Taylor E, ed. ADHD. Mac Keith Press; 2007.
- Gringras P. Melatonin. In: Taylor DM, Barnes TRE, Young AH, ed. The Maudsley Prescribing Guidelines in Psychiatry 14th Edition. Wiley-Blackwell. 2021
- Gringras P. Melatonin. In: Taylor DM, Barnes TRE, Young AH, ed. The Maudsley Prescribing Guidelines in Psychiatry 15th Edition. Wiley-Blackwell. 2025
- Baird G, Gringras P. Investigation of developmental delay. In: Rutter M, ed. Rutter’s Child and Adolescent Psychiatry and Psychology. Cambridge University Press; 2008.
- Gringras P. Autism for primary care. In: Bannon M, ed. Paediatrics for Primary Care. Cambridge University Press; 2004.
- Hartley L, Salt A, Dorling J, Gringras P. Investigation of children with developmental delay. In: Moyer VA, Elliot EY, Davies R, ed. Evidence‑Based Paediatrics. BMJ Books; 2004.
- Gringras P. Self‑injury in learning disability. In: Nunn K, ed. Clinical Psychopharmacology for the Clinician. Westmead; 2003.
- Gringras P, Tomlin S. Recommended management of sleep problems in childhood. Prescriber. 2007;18(6):19–30.
- Gringras P. When to use drugs to help sleep. Archives of Disease in Childhood. 2008;93(11):976–981.
- Gringras P. Sleep in neurodevelopmental disorders. Sleep Medicine Textbook, 2nd edition. IN: Bassetti C, McNicholas W, Paunio T, Peigneux P, ed. European Sleep Research Society (ESRS) 2021
- Gringras P Paediatric Neurodisability and Sleep. In: Leschziner G, ed. Oxford Handbook of Sleep Medicine. OUP Oxford. 2022
Reviews, Chapters, Monographs & Editorials
- Gringras P. Sleep and its disturbances in autistic spectrum disorders. In: Sheldon SH, Kryger MH, Ferber R, eds. Principles and Practice of Pediatric Sleep Medicine. 2nd ed. Saunders; 2014.
- Gringras P. Sleep and its disturbances in autistic spectrum disorders. In: Sheldon SH, Kryger MH, Gozal D, Canapari D, Oyebile-Chidi TO, eds. Principles and Practice of Pediatric Sleep Medicine. 3rd ed. Elsevier; 2024.
- Gringras P. Sleep disorders and ADHD. In: Taylor E, ed. ADHD. Mac Keith Press; 2007.
- Gringras P. Melatonin. In: Taylor DM, Barnes TRE, Young AH, ed. The Maudsley Prescribing Guidelines in Psychiatry 14th Edition. Wiley-Blackwell. 2021
- Gringras P. Melatonin. In: Taylor DM, Barnes TRE, Young AH, ed. The Maudsley Prescribing Guidelines in Psychiatry 15th Edition. Wiley-Blackwell. 2025
- Baird G, Gringras P. Investigation of developmental delay. In: Rutter M, ed. Rutter’s Child and Adolescent Psychiatry and Psychology. Cambridge University Press; 2008.
- Gringras P. Autism for primary care. In: Bannon M, ed. Paediatrics for Primary Care. Cambridge University Press; 2004.
- Hartley L, Salt A, Dorling J, Gringras P. Investigation of children with developmental delay. In: Moyer VA, Elliot EY, Davies R, ed. Evidence‑Based Paediatrics. BMJ Books; 2004.
- Gringras P. Self‑injury in learning disability. In: Nunn K, ed. Clinical Psychopharmacology for the Clinician. Westmead; 2003.
- Gringras P, Tomlin S. Recommended management of sleep problems in childhood. Prescriber. 2007;18(6):19–30.
- Gringras P. When to use drugs to help sleep. Archives of Disease in Childhood. 2008;93(11):976–981.
- Gringras P. Sleep in neurodevelopmental disorders. Sleep Medicine Textbook, 2nd edition. IN: Bassetti C, McNicholas W, Paunio T, Peigneux P, ed. European Sleep Research Society (ESRS) 2021
- Gringras P. Paediatric Neurodisability and Sleep. In: Leschziner G, ed. Oxford Handbook of Sleep Medicine. OUP Oxford. 2022
Books/textbooks for the medical, scientific and lay community
- Gringras P, Pal DK MRCPCH Part 2 Paediatric Practice Exams. 1st ed. Pastest; 1993.
- Gringras P, Pal DK, Greenburg M. MRCPCH Part 2 Paediatric Practice Exams. 2nd eds. Pastest; 1999.
- Gringras P. 2025 Why Don’t Children Sleep? Macmillan Picador
Selected Posters from Professional Meetings over last three years
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- 2025 – Narcolepsy Revolution: Interpretable machine‑learning for automated sleep stage classification in narcolepsy and hypersomnia – World Sleep Congress – poster (AS‑WS‑2025‑02754). With Rajaram A; Orkouby HO; Senior E; Birdseye A; Pérez Carbonell L; Rossor T; Gringras P; Bartsch U.
- 2025 – Early insights from the Mind & Skin trial – preliminary neurocognitive and dermatology outcomes – British Association of Dermatologists Annual Meeting – British Journal of Dermatology, Abstract PA21 – poster.
- 2024 – The Narcolepsy Revolution – an ambulatory home wearable with AI – World Sleep / European Sleep Research Society – Journal of Sleep Research – abstract/poster.
- 2019 – Developing an online behaviourally‑based sleep intervention for parents of children with epilepsy (CASTLE COSI) – Journal of Sleep Research – Abstract P011 – poster.
- 2014 – Prevalence of obstructive sleep apnoea in young children with Down syndrome – a domiciliary cardiorespiratory study – Journal of Sleep Research – Abstract P999 – poster.